Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data

BACKGROUND: Genome-wide association studies (GWAS) have identified several hundred susceptibility loci for type 2 diabetes (T2D). One critical, but unresolved, issue concerns the extent to which the mechanisms through which these diverse signals influencing T2D predisposition converge on a limited s...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Fernández-Tajes, Juan, Gaulton, Kyle J., van de Bunt, Martijn, Torres, Jason, Thurner, Matthias, Mahajan, Anubha, Gloyn, Anna L., Lage, Kasper, McCarthy, Mark I.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436236/
https://ncbi.nlm.nih.gov/pubmed/30914061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0628-8
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