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A Multi-omic Integrative Scheme Characterizes Tissues of Action at Loci Associated with Type 2 Diabetes

Resolving the molecular processes that mediate genetic risk remains a challenge because most disease-associated variants are non-coding and functional characterization of these signals requires knowledge of the specific tissues and cell-types in which they operate. To address this challenge, we deve...

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Publicado en:Am J Hum Genet
Autores principales: Torres, Jason M., Abdalla, Moustafa, Payne, Anthony, Fernandez-Tajes, Juan, Thurner, Matthias, Nylander, Vibe, Gloyn, Anna L., Mahajan, Anubha, McCarthy, Mark I.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820628/
https://ncbi.nlm.nih.gov/pubmed/33186544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.10.009
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