Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS)

Yazar: Drewry, David H., Willson, Timothy M., Zuercher, William J.
Yayımlandı Curr Top Med Chem (2014)

Transactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating Element

Yazar: Arao, Yukitomo, Coons, Laurel A., Zuercher, William J., Korach, Kenneth S.
Yayımlandı J Biol Chem (2015)

Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor

Yazar: Zhang, Cunyu, Creech, Katrina L., Zuercher, William J., Willson, Timothy M.
Yayımlandı Sci Rep (2019)

A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction

Yazar: Drewry, David H., Wells, Carrow I., Zuercher, William J., Willson, Timothy M.
Yayımlandı SLAS Discov (2019)

New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I–Interacting Kinase (TNNi3K)

Yazar: Asquith, Christopher R. M., Laitinen, Tuomo, Wells, Carrow I., Tizzard, Graham J., Zuercher, William J.
Yayımlandı Molecules (2020)

Crystal Structure of the PXR-T1317 Complex Provides a Scaffold to Examine the Potential for Receptor Antagonism

Yazar: Xue, Yu, Chao, Esther, Zuercher, William J., Willson, Timothy M., Collins, Jon L., Redinbo, Matthew R.
Baskı/Yayın Bilgisi 2006

The metabolic regulator ERRα, a downstream target of HER2/IGF-1, as a therapeutic target in breast cancer

Yazar: Chang, Ching-yi, Kazmin, Dmitri, Jasper, Jeff S., Kunder, Rebecca, Zuercher, William J., McDonnell, Donald P.
Baskı/Yayın Bilgisi 2011

Profile of the GSK Published Protein Kinase Inhibitor Set Across ATP-Dependent and-Independent Luciferases: Implications for Reporter-Gene Assays

Yazar: Dranchak, Patricia, MacArthur, Ryan, Guha, Rajarshi, Zuercher, William J., Drewry, David H., Auld, Douglas S., Inglese, James
Baskı/Yayın Bilgisi 2013

Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines

Yazar: Asquith, Christopher R. M., Fleck, Neil, Torrice, Chad D., Crona, Daniel J., Grundner, Christoph, Zuercher, William J.
Yayımlandı Bioorg Med Chem Lett (2019)

Identifying the target of an antiparasitic compound in Toxoplasma using thermal proteome profiling

Yazar: Herneisen, Alice L., Sidik, Saima M., Markus, Benedikt M., Drewry, David H., Zuercher, William J., Lourido, Sebastian
Yayımlandı ACS Chem Biol (2020)

High-throughput screening of a GlaxoSmithKline protein kinase inhibitor set identifies an inhibitor of human cytomegalovirus replication that prevents CREB and histone H3 post-tran...

Yazar: Khan, Amina S, Murray, Matthew J, Ho, Catherine M. K, Zuercher, William J, Reeves, Matthew B, Strang, Blair L
Yayımlandı J Gen Virol (2017)

Nuclear Receptor Signaling Atlas (): hyperlinking the nuclear receptor signaling community

Yazar: Lanz, Rainer B., Jericevic, Zeljko, Zuercher, William J., Watkins, Chris, Steffen, David L., Margolis, Ronald, McKenna, Neil J.
Baskı/Yayın Bilgisi 2006

A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA

Yazar: Schaenzer, Adam J., Wlodarchak, Nathan, Drewry, David H., Zuercher, William J., Rose, Warren E., Striker, Rob, Sauer, John-Demian
Yayımlandı J Biol Chem (2017)

Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series

Yazar: Wang, Christopher B., Lorente-Macías, Álvaro, Wells, Carrow, Pickett, Julie E., Picado, Alfredo, Zuercher, William J., Axtman, Alison D.
Yayımlandı RSC Med Chem (2020)

Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data

Yazar: Strang, Blair L., Asquith, Christopher R. M., Moshrif, Hanan F., Ho, Catherine M-K, Zuercher, William J., Al-Ali, Hassan
Yayımlandı PLoS One (2018)

GW779439X and Its Pyrazolopyridazine Derivatives Inhibit the Serine/Threonine Kinase Stk1 and Act As Antibiotic Adjuvants against β-Lactam-Resistant Staphylococcus aureus

Yazar: Schaenzer, Adam J., Wlodarchak, Nathan, Drewry, David H., Zuercher, William J., Rose, Warren E., Ferrer, Carla A., Sauer, John-Demian, Striker, Rob
Yayımlandı ACS Infect Dis (2018)

Identification of drug modifiers for RYR1-related myopathy using a multi-species discovery pipeline

Yazar: Volpatti, Jonathan R, Endo, Yukari, Knox, Jessica, Groom, Linda, Brennan, Stephanie, Noche, Ramil, Zuercher, William J, Roy, Peter, Dirksen, Robert T, Dowling, James J
Yayımlandı eLife (2020)

Ligand-Dependent Regulation of the Activity of the Orphan Nuclear Receptor, Small Heterodimer Partner (SHP), in the Repression of Bile Acid Biosynthetic CYP7A1 and CYP8B1 Genes

Yazar: Miao, Ji, Choi, Sung-E, Seok, Sun Mi, Yang, Linda, Zuercher, William J., Xu, Yong, Willson, Timothy M., Xu, H. Eric, Kemper, Jongsook Kim
Baskı/Yayın Bilgisi 2011

On the intractability of estrogen-related receptor α as a target for activation by small molecules

Yazar: Hyatt, Stephen M., Lockamy, Elizabeth, Stein, Rebecca A., McDonnell, Donald P., Miller, Aaron B., Orband-Miller, Lisa A., Willson, Timothy M., Zuercher, William J.
Baskı/Yayın Bilgisi 2007

Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System

Yazar: Carabajal, María Ayelén, Asquith, Christopher R. M., Laitinen, Tuomo, Tizzard, Graham J., Yim, Lucía, Rial, Analía, Chabalgoity, José A., Zuercher, William J., García Véscovi, Eleonora
Yayımlandı Antimicrob Agents Chemother (2019)