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Transactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating Element

ERα has a ligand-dependent transactivation function in the ligand binding domain of ERα C terminus (AF-2) and a ligand-independent activation function in the N terminus (AF-1). It is still not fully understood how AF-1 and AF-2 activities are regulated cooperatively by ligands. To evaluate the AF-1...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Arao, Yukitomo, Coons, Laurel A., Zuercher, William J., Korach, Kenneth S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498094/
https://ncbi.nlm.nih.gov/pubmed/26028650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638650
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