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A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA

Bacterial signaling systems such as protein kinases and quorum sensing have become increasingly attractive targets for the development of novel antimicrobial agents in a time of rising antibiotic resistance. The family of bacterial Penicillin-binding-protein And Serine/Threonine kinase-Associated (P...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Schaenzer, Adam J., Wlodarchak, Nathan, Drewry, David H., Zuercher, William J., Rose, Warren E., Striker, Rob, Sauer, John-Demian
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641865/
https://ncbi.nlm.nih.gov/pubmed/28821610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808600
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