Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System

The rapid emergence of multidrug resistance among bacterial pathogens has become a significant challenge to human health in our century. Therefore, development of next-generation antibacterial compounds is an urgent need. Two-component signal transduction systems (TCS) are stimulus-response coupling...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Carabajal, María Ayelén, Asquith, Christopher R. M., Laitinen, Tuomo, Tizzard, Graham J., Yim, Lucía, Rial, Analía, Chabalgoity, José A., Zuercher, William J., García Véscovi, Eleonora
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Biologic Response Modifiers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187569/
https://ncbi.nlm.nih.gov/pubmed/31611347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01744-19
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