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Identifying the target of an antiparasitic compound in Toxoplasma using thermal proteome profiling
Apicomplexan parasites include the causative agents of malaria and toxoplasmosis. Cell-based screens in Toxoplasma previously identified a chemical modulator of calcium signaling (ENH1) that blocked parasite egress from host cells and exhibited potent antiparasitic activity. To identify the targets...
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| Vydáno v: | ACS Chem Biol |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7585386/ https://ncbi.nlm.nih.gov/pubmed/32597628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00369 |
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