Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS)

द्वारा Drewry, David H., Willson, Timothy M., Zuercher, William J.
में प्रकाशित Curr Top Med Chem (2014)

Transactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating Element

द्वारा Arao, Yukitomo, Coons, Laurel A., Zuercher, William J., Korach, Kenneth S.
में प्रकाशित J Biol Chem (2015)

Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor

द्वारा Zhang, Cunyu, Creech, Katrina L., Zuercher, William J., Willson, Timothy M.
में प्रकाशित Sci Rep (2019)

A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction

द्वारा Drewry, David H., Wells, Carrow I., Zuercher, William J., Willson, Timothy M.
में प्रकाशित SLAS Discov (2019)

New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I–Interacting Kinase (TNNi3K)

द्वारा Asquith, Christopher R. M., Laitinen, Tuomo, Wells, Carrow I., Tizzard, Graham J., Zuercher, William J.
में प्रकाशित Molecules (2020)

Crystal Structure of the PXR-T1317 Complex Provides a Scaffold to Examine the Potential for Receptor Antagonism

द्वारा Xue, Yu, Chao, Esther, Zuercher, William J., Willson, Timothy M., Collins, Jon L., Redinbo, Matthew R.
प्रकाशित 2006

The metabolic regulator ERRα, a downstream target of HER2/IGF-1, as a therapeutic target in breast cancer

द्वारा Chang, Ching-yi, Kazmin, Dmitri, Jasper, Jeff S., Kunder, Rebecca, Zuercher, William J., McDonnell, Donald P.
प्रकाशित 2011

Profile of the GSK Published Protein Kinase Inhibitor Set Across ATP-Dependent and-Independent Luciferases: Implications for Reporter-Gene Assays

द्वारा Dranchak, Patricia, MacArthur, Ryan, Guha, Rajarshi, Zuercher, William J., Drewry, David H., Auld, Douglas S., Inglese, James
प्रकाशित 2013

Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines

द्वारा Asquith, Christopher R. M., Fleck, Neil, Torrice, Chad D., Crona, Daniel J., Grundner, Christoph, Zuercher, William J.
में प्रकाशित Bioorg Med Chem Lett (2019)

Identifying the target of an antiparasitic compound in Toxoplasma using thermal proteome profiling

द्वारा Herneisen, Alice L., Sidik, Saima M., Markus, Benedikt M., Drewry, David H., Zuercher, William J., Lourido, Sebastian
में प्रकाशित ACS Chem Biol (2020)

High-throughput screening of a GlaxoSmithKline protein kinase inhibitor set identifies an inhibitor of human cytomegalovirus replication that prevents CREB and histone H3 post-tran...

द्वारा Khan, Amina S, Murray, Matthew J, Ho, Catherine M. K, Zuercher, William J, Reeves, Matthew B, Strang, Blair L
में प्रकाशित J Gen Virol (2017)

Nuclear Receptor Signaling Atlas (): hyperlinking the nuclear receptor signaling community

द्वारा Lanz, Rainer B., Jericevic, Zeljko, Zuercher, William J., Watkins, Chris, Steffen, David L., Margolis, Ronald, McKenna, Neil J.
प्रकाशित 2006

A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA

द्वारा Schaenzer, Adam J., Wlodarchak, Nathan, Drewry, David H., Zuercher, William J., Rose, Warren E., Striker, Rob, Sauer, John-Demian
में प्रकाशित J Biol Chem (2017)

Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series

द्वारा Wang, Christopher B., Lorente-Macías, Álvaro, Wells, Carrow, Pickett, Julie E., Picado, Alfredo, Zuercher, William J., Axtman, Alison D.
में प्रकाशित RSC Med Chem (2020)

Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data

द्वारा Strang, Blair L., Asquith, Christopher R. M., Moshrif, Hanan F., Ho, Catherine M-K, Zuercher, William J., Al-Ali, Hassan
में प्रकाशित PLoS One (2018)

GW779439X and Its Pyrazolopyridazine Derivatives Inhibit the Serine/Threonine Kinase Stk1 and Act As Antibiotic Adjuvants against β-Lactam-Resistant Staphylococcus aureus

द्वारा Schaenzer, Adam J., Wlodarchak, Nathan, Drewry, David H., Zuercher, William J., Rose, Warren E., Ferrer, Carla A., Sauer, John-Demian, Striker, Rob
में प्रकाशित ACS Infect Dis (2018)

Identification of drug modifiers for RYR1-related myopathy using a multi-species discovery pipeline

द्वारा Volpatti, Jonathan R, Endo, Yukari, Knox, Jessica, Groom, Linda, Brennan, Stephanie, Noche, Ramil, Zuercher, William J, Roy, Peter, Dirksen, Robert T, Dowling, James J
में प्रकाशित eLife (2020)

Ligand-Dependent Regulation of the Activity of the Orphan Nuclear Receptor, Small Heterodimer Partner (SHP), in the Repression of Bile Acid Biosynthetic CYP7A1 and CYP8B1 Genes

द्वारा Miao, Ji, Choi, Sung-E, Seok, Sun Mi, Yang, Linda, Zuercher, William J., Xu, Yong, Willson, Timothy M., Xu, H. Eric, Kemper, Jongsook Kim
प्रकाशित 2011

On the intractability of estrogen-related receptor α as a target for activation by small molecules

द्वारा Hyatt, Stephen M., Lockamy, Elizabeth, Stein, Rebecca A., McDonnell, Donald P., Miller, Aaron B., Orband-Miller, Lisa A., Willson, Timothy M., Zuercher, William J.
प्रकाशित 2007

Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System

द्वारा Carabajal, María Ayelén, Asquith, Christopher R. M., Laitinen, Tuomo, Tizzard, Graham J., Yim, Lucía, Rial, Analía, Chabalgoity, José A., Zuercher, William J., García Véscovi, Eleonora
में प्रकाशित Antimicrob Agents Chemother (2019)