Control of cellular homeostasis: organelles take the pilot's seat

מאת Tooze, Sharon, Zoncu, Roberto
הוצא לאור ב Mol Biol Cell (2015)

Cell Biology: the TASCC of secretion

מאת Zoncu, Roberto, Sabatini, David M.
יצא לאור 2011

The lysosome as a command-and-control center for cellular metabolism

מאת Lim, Chun-Yan, Zoncu, Roberto
הוצא לאור ב J Cell Biol (2016)

Emerging roles for the lysosome in lipid metabolism

מאת Thelen, Ashley M., Zoncu, Roberto
הוצא לאור ב Trends Cell Biol (2017)

The Lysosome at the intersection of cellular growth and destruction.

מאת Shin, Hijai R., Zoncu, Roberto
הוצא לאור ב Dev Cell (2020)

Amino acids and mTORC1: from lysosomes to disease

מאת Efeyan, Alejo, Zoncu, Roberto, Sabatini, David M.
יצא לאור 2012

mTOR: from growth signal integration to cancer, diabetes and ageing

מאת Zoncu, Roberto, Sabatini, David M., Efeyan, Alejo
יצא לאור 2010

Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo

מאת Sheen, Joon-Ho, Zoncu, Roberto, Kim, Dohoon, Sabatini, David M.
יצא לאור 2011

An expanded Ragulator is a GEF for the Rag GTPases that signal amino acid levels to mTORC1

מאת Bar-Peled, Liron, Schweitzer, Lawrence D., Zoncu, Roberto, Sabatini, David M.
יצא לאור 2012

Structure of the C9orf72 Arf GAP complex haploinsufficient in ALS and FTD

מאת Su, Ming-Yuan, Fromm, Simon A., Zoncu, Roberto, Hurley, James H.
הוצא לאור ב Nature (2020)

Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages

מאת Perera, Rushika M., Zoncu, Roberto, Lucast, Louise, De Camilli, Pietro, Toomre, Derek
יצא לאור 2006

Dynamics and architecture of the NRBF2-containing phosphatidylinositol 3-kinase complex I of autophagy

מאת Young, Lindsey N., Cho, Kelvin, Lawrence, Rosalie, Zoncu, Roberto, Hurley, James H.
הוצא לאור ב Proc Natl Acad Sci U S A (2016)

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the Vacuolar H(+)-ATPase

מאת Zoncu, Roberto, Bar-Peled, Liron, Efeyan, Alejo, Wang, Shuyu, Sancak, Yasemin, Sabatini, David M.
יצא לאור 2011

Identification of an Oncogenic RAB Protein

מאת Wheeler, Douglas B., Zoncu, Roberto, Root, David E., Sabatini, David M., Sawyers, Charles L.
הוצא לאור ב Science (2015)

A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

מאת Zoncu, Roberto, Perera, Rushika M, Balkin, Daniel M, Pirruccello, Michelle, Toomre, Derek, De Camilli, Pietro
יצא לאור 2009

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

מאת Sancak, Yasemin, Bar-Peled, Liron, Zoncu, Roberto, Markhard, Andrew L., Nada, Shigeyuki, Sabatini, David M.
יצא לאור 2010

NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease

מאת Bindesbøll, Christian, Aas, Aleksander, Ogmundsdottir, Margret Helga, Pankiv, Serhiy, Reine, Trine, Zoncu, Roberto, Simonsen, Anne
הוצא לאור ב Sci Rep (2020)

Dynamics of mTORC1 activation in response to amino acids

מאת Manifava, Maria, Smith, Matthew, Rotondo, Sergio, Walker, Simon, Niewczas, Izabella, Zoncu, Roberto, Clark, Jonathan, Ktistakis, Nicholas T
הוצא לאור ב eLife (2016)

PhotoGate microscopy to track single molecules in crowded environments

מאת Belyy, Vladislav, Shih, Sheng-Min, Bandaria, Jigar, Huang, Yongjian, Lawrence, Rosalie E., Zoncu, Roberto, Yildiz, Ahmet
הוצא לאור ב Nat Commun (2017)

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics

מאת Nakatsu, Fubito, Perera, Rushika M., Lucast, Louise, Zoncu, Roberto, Domin, Jan, Gertler, Frank B., Toomre, Derek, De Camilli, Pietro
יצא לאור 2010