Application of oxime-diversification to optimize ligand interactions within a cryptic pocket of the polo-like kinase 1 polo-box domain

Por Zhao, Xue Zhi, Hymel, David, Burke, Terrence R.
Publicado no Bioorg Med Chem Lett (2016)

Diketoacid – Genre HIV-1 Integrase Inhibitors Containing Enantiomeric Arylamide Functionality

Por Zhao, Xue Zhi, Maddali, Kasthuraiah, Marchand, Christophe, Pommier, Yves, Burke, Terrence R.
Publicado em 2009

Comparison of metal-dependent catalysis by HIV-1 and ASV integrase proteins using a new and rapid, moderate throughput assay for joining activity in solution

Por Andrake, Mark D, Ramcharan, Joseph, Merkel, George, Zhao, Xue Zhi, Burke, Terrence R, Skalka, Anna Marie
Publicado em 2009

MK-0536 Inhibits HIV-1 Integrases Resistant to Raltegravir

Por Métifiot, Mathieu, Johnson, Barry, Smith, Steven, Zhao, Xue Zhi, Marchand, Christophe, Burke, Terrence, Hughes, Stephen, Pommier, Yves
Publicado em 2011

Examination of halogen substituent effects on HIV-1 integrase inhibitors derived from 2,3-dihydro-6,7-dihydroxy-1H-isoindol-1-ones and 4,5-dihydroxy-1H-isoindole-1,3(2H)-diones

Por Zhao, Xue Zhi, Maddali, Kasthuraiah, Vu, B. Christie, Marchand, Christophe, Hughes, Stephen H., Pommier, Yves, Burke, Terrence R.
Publicado em 2009

Analysis of the prognostic risk factors of idiopathic membranous nephropathy using a new surrogate end-point

Por ZHANG, BO, CHENG, MING, YANG, MING, HAN, SHUAI, ZHANG, YING-HUI, SHI, HONG-GUANG, ZHU, LIANG, ZHAO, XUE-ZHI
Publicado no Biomed Rep (2016)

Bicyclic 1-Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide-Containing HIV-1 Integrase Inhibitors Having High Antiviral Potency against Cells Harboring Raltegravir-Resistant Integra...

Por Zhao, Xue Zhi, Smith, Steven J., Métifiot, Mathieu, Johnson, Barry C., Marchand, Christophe, Pommier, Yves, Hughes, Stephen H., Burke, Terrence R.
Publicado em 2014

4-Amino-1-hydroxy-2-oxo-1,8-naphthyridine-Containing Compounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV-1

Por Zhao, Xue Zhi, Smith, Steven J., Métifiot, Mathieu, Marchand, Christophe, Boyer, Paul L., Pommier, Yves, Hughes, Stephen H., Burke, Terrence R.
Publicado em 2014

Correction to 4-Amino-1-hydroxy-2-oxo-1,8-naphthyridine-Containing Compounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV-1

Por Zhao, Xue Zhi, Smith, Steven J., Métifiot, Mathieu, Marchand, Christophe, Boyer, Paul L., Pommier, Yves, Hughes, Stephen H., Burke, Terrence R.
Publicado no J Med Chem (2014)

Selectivity for strand-transfer over 3′-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme–DNA interactions in the active s...

Por Métifiot, Mathieu, Johnson, Barry C., Kiselev, Evgeny, Marler, Laura, Zhao, Xue Zhi, Burke, Terrence R., Marchand, Christophe, Hughes, Stephen H., Pommier, Yves
Publicado no Nucleic Acids Res (2016)

Development of Tricyclic Hydroxy-1H-pyrrolopyridine-trione Containing HIV-1 Integrase Inhibitors

Por Zhao, Xue Zhi, Maddali, Kasthuraiah, Metifiot, Mathieu, Smith, Steven J., Vu, B. Christie, Marchand, Christophe, Hughes, Stephen H., Pommier, Yves, Burke, Terrence R.
Publicado em 2011

6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 Integrase Inhibitors

Por Zhao, Xue Zhi, Maddali, Kasthuraiah, Smith, Steven J., Métifiot, Mathieu, Johnson, Barry C., Marchand, Christophe, Hughes, Stephen H., Pommier, Yves, Burke, Terrence R.
Publicado em 2012

HIV Integrase Inhibitors Block Replication of Alpha-, Beta-, and Gammaherpesviruses

Por Yan, Zhipeng, Bryant, Kevin F., Gregory, Sean M., Angelova, Magdalena, Dreyfus, David H., Zhao, Xue Zhi, Coen, Donald M., Burke, Terrence R., Knipe, David M.
Publicado em 2014

Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction

Por Im, Young Jun, Kuo, Lillian, Ren, Xuefeng, Burgos, Patricia V., Zhao, Xue Zhi, Liu, Fa, Burke, Terrence R., Bonifacino, Juan S., Freed, Eric O., Hurley, James H.
Publicado em 2010

Activities, crystal structures and molecular dynamics of dihydro-1H-isoindole derivatives, inhibitors of HIV-1 integrase

Por Métifiot, Mathieu, Maddali, Kasthuraiah, Johnson, Barry C., Hare, Stephen, Smith, Steven J., Zhao, XueZhi, Marchand, Christophe, Burke, Terrence R., Hughes, Stephen H., Cherepanov, Peter, Pommier, Yves
Publicado em 2012

HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant Mutant Integrases

Por Zhao, Xue Zhi, Smith, Steven J., Maskell, Daniel P., Metifiot, Mathieu, Pye, Valerie E., Fesen, Katherine, Marchand, Christophe, Pommier, Yves, Cherepanov, Peter, Hughes, Stephen H., Burke, Terrence R.
Publicado no ACS Chem Biol (2016)

Scientific Publications in Nephrology and Urology Journals from Chinese Authors in East Asia: A 10-Year Survey of the Literature

Por Xu, Jing, Mao, Zhi-Guo, Kong, Mei, Hu, Liang-Hao, Ye, Chao-Yang, Xu, Cheng-Gang, Rong, Shu, Sun, Li-Jun, Wu, Jun, Dai, Bing, Chen, Dong-Ping, Zhu, Yu-Xian, Zhang, Yi-Xiang, Zhang, Yu-Qiang, Zhao, Xue-Zhi, Mei, Chang-Lin
Publicado em 2011