Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88

por Zhang, Huajia, Rodriguez, Sonia, Wang, Lin, Wang, Soujuan, Serezani, Henrique, Kapur, Reuben, Cardoso, Angelo A., Carlesso, Nadia
Publicado no Stem Cell Reports (2016)

Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone

por Tu, Xiaolin, Delgado-Calle, Jesus, Condon, Keith W., Maycas, Marta, Zhang, Huajia, Carlesso, Nadia, Taketo, Makoto M., Burr, David B., Plotkin, Lilian I., Bellido, Teresita
Publicado no Proc Natl Acad Sci U S A (2015)

Cooperation of oncolytic virotherapy with VEGF-neutralizing antibody treatment in IDH wildtype glioblastoma depends on MMP9

por Wirsching, Hans-Georg, Arora, Sonali, Zhang, Huajia, Szulzewsky, Frank, Cimino, Patrick J, Quéva, Christophe, Houghton, A McGarry, Glorioso, Joseph C, Weller, Michael, Holland, Eric C
Publicado no Neuro Oncol (2019)

Chronic Obstructive Pulmonary Disease Alters Immune Cell Composition and Immune Checkpoint Inhibitor Efficacy in Non–Small Cell Lung Cancer

por Mark, Nicholas M., Kargl, Julia, Busch, Stephanie E., Yang, Grace H. Y., Metz, Heather E., Zhang, Huajia, Hubbard, Jesse J., Pipavath, Sudhakar N. J., Madtes, David K., Houghton, A. McGarry
Publicado no Am J Respir Crit Care Med (2018)

TMIC-05. ABSCOPAL IMMUNE RESPONSE IN GLIOBLASTOMA ELICITED BY MIR124-ATTENUATED ONCOLYTIC HERPES SIMPLEX VIRUS 1 ARMED WITH UL16 BINDING PROTEIN 3

por Wirsching, Hans-Georg, Zhang, Huajia, Grandi, Paola, Arora, Sonali, Cimino, Patrick J, Campbell, Jean S, Szulzewsky, Frank, Pattwell, Siobhan S, Ene, Chibawanye, Kumasaka, Debrah, Pierce, Robert H, Finer, Mitchell, Queva, Christophe, Houghton, A McGarry, Holland, Eric
Publicado no Neuro Oncol (2018)

CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche

por Chitteti, Brahmananda Reddy, Kobayashi, Michihiro, Cheng, Yinghua, Zhang, Huajia, Poteat, Bradley A., Broxmeyer, Hal E., Pelus, Louis M., Hanenberg, Helmut, Zollman, Amy, Kamocka, Malgorzata M., Carlesso, Nadia, Cardoso, Angelo A., Kacena, Melissa A., Srour, Edward F.
Publicado em 2014

MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity

por Grunblatt, Eli, Wu, Nan, Zhang, Huajia, Liu, Xiaoli, Norton, Justin P., Ohol, Yamini, Leger, Paul, Hiatt, Joseph B., Eastwood, Emily C., Thomas, Rhiana, Ibrahim, Ali H., Jia, Deshui, Basom, Ryan, Eaton, Keith D., Martins, Renato, Houghton, A. McGarry, MacPherson, David
Publicado no Genes Dev (2020)

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

por Rodriguez, Sonia, Abundis, Christina, Boccalatte, Francesco, Mehrotra, Purvi, Chiang, Mark Y., Yui, Mary A., Wang, Lin, Zhang, Huajia, Zollman, Amy, Bonfim-Silva, Ricardo, Kloetgen, Andreas, Palmer, Joycelynne, Sandusky, George, Wunderlich, Mark, Kaplan, Mark H., Mulloy, James C., Marcucci, Guido, Aifantis, Iannis, Cardoso, Angelo A., Carlesso, Nadia
Publicado no Leukemia (2019)

Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB dependent manner

por Wang, Lin, Zhang, Huajia, Rodriguez, Sonia, Cao, Liyun, Parish, Jonathan, Mumaw, Christen, Zollman, Amy, Kamocka, Gosia, Mu, Jian, Chen, Danny Z., Srour, Edward F., Chitteti, Brahmananda R., HogenEsch, Harm, Tu, Xiaolin, Bellido, Teresita M., Boswell, Scott, Manshouri, Taghi, Verstovsek, Srdan, Yoder, Mervin C., Kapur, Reuben, Cardoso, Angelo A., Carlesso, Nadia
Publicado no Cell Stem Cell (2014)

Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC

por Kargl, Julia, Zhu, Xiaodong, Zhang, Huajia, Yang, Grace H. Y., Friesen, Travis J., Shipley, Melissa, Maeda, Dean Y., Zebala, John A., McKay-Fleisch, Jill, Meredith, Gavin, Mashadi-Hossein, Afshin, Baik, Christina, Pierce, Robert H., Redman, Mary W., Thompson, Jeffrey C., Albelda, Steven M., Bolouri, Hamid, Houghton, A. McGarry
Publicado no JCI Insight (2019)

Anti–PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma

por Ene, Chibawanye I, Kreuser, Shannon A, Jung, Miyeon, Zhang, Huajia, Arora, Sonali, White Moyes, Kara, Szulzewsky, Frank, Barber, Jason, Cimino, Patrick J, Wirsching, Hans-Georg, Patel, Anoop, Kong, Paul, Woodiwiss, Timothy R, Durfy, Sharon J, Houghton, A McGarry, Pierce, Robert H, Parney, Ian F, Crane, Courtney A, Holland, Eric C
Publicado no Neuro Oncol (2020)

Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma

por Wirsching, Hans-Georg, Zhang, Huajia, Szulzewsky, Frank, Arora, Sonali, Grandi, Paola, Cimino, Patrick J., Amankulor, Nduka, Campbell, Jean S., McFerrin, Lisa, Pattwell, Siobhan S., Ene, Chibawanye, Hicks, Alexandra, Ball, Michael, Yan, James, Zhang, Jenny, Kumasaka, Debrah, Pierce, Robert H., Weller, Michael, Finer, Mitchell, Quéva, Christophe, Glorioso, Joseph C., Houghton, A. McGarry, Holland, Eric C.
Publicado no JCI Insight (2019)