Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB dependent manner

MicroRNA (miR)-155 has been implicated in regulating inflammatory responses and tumorigenesis, but its precise role in linking inflammation and cancer has remained elusive. Here, we identify a connection between miR-155 and Notch signaling in this context. Loss of Notch signaling in the bone marrow...

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Publicado no:Cell Stem Cell
Main Authors: Wang, Lin, Zhang, Huajia, Rodriguez, Sonia, Cao, Liyun, Parish, Jonathan, Mumaw, Christen, Zollman, Amy, Kamocka, Gosia, Mu, Jian, Chen, Danny Z., Srour, Edward F., Chitteti, Brahmananda R., HogenEsch, Harm, Tu, Xiaolin, Bellido, Teresita M., Boswell, Scott, Manshouri, Taghi, Verstovsek, Srdan, Yoder, Mervin C., Kapur, Reuben, Cardoso, Angelo A., Carlesso, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398997/
https://ncbi.nlm.nih.gov/pubmed/24996169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.04.021
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