Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB dependent manner

MicroRNA (miR)-155 has been implicated in regulating inflammatory responses and tumorigenesis, but its precise role in linking inflammation and cancer has remained elusive. Here, we identify a connection between miR-155 and Notch signaling in this context. Loss of Notch signaling in the bone marrow...

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Publicado en:Cell Stem Cell
Autores principales: Wang, Lin, Zhang, Huajia, Rodriguez, Sonia, Cao, Liyun, Parish, Jonathan, Mumaw, Christen, Zollman, Amy, Kamocka, Gosia, Mu, Jian, Chen, Danny Z., Srour, Edward F., Chitteti, Brahmananda R., HogenEsch, Harm, Tu, Xiaolin, Bellido, Teresita M., Boswell, Scott, Manshouri, Taghi, Verstovsek, Srdan, Yoder, Mervin C., Kapur, Reuben, Cardoso, Angelo A., Carlesso, Nadia
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398997/
https://ncbi.nlm.nih.gov/pubmed/24996169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.04.021
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