Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockade of mTOR and NF-κB

Por Costa, Lara F., Balcells, Mercedes, Edelman, Elazer R., Nadler, Lee M., Cardoso, Angelo A.
Publicado em 2006

Activation of PI3K Is Indispensable for Interleukin 7–mediated Viability, Proliferation, Glucose Use, and Growth of T Cell Acute Lymphoblastic Leukemia Cells

Por Barata, Joao T., Silva, Ana, Brandao, Joana G., Nadler, Lee M., Cardoso, Angelo A., Boussiotis, Vassiliki A.
Publicado em 2004

Smooth muscle cells orchestrate the endothelial cell response to flow and injury

Por Balcells, Mercedes, Martorell, Jordi, Olive, Carla, Santacana, Marina, Chitalia, Vipul, Cardoso, Angelo A., Edelman, Elazer R.
Publicado em 2010

Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88

Por Zhang, Huajia, Rodriguez, Sonia, Wang, Lin, Wang, Soujuan, Serezani, Henrique, Kapur, Reuben, Cardoso, Angelo A., Carlesso, Nadia
Publicado no Stem Cell Reports (2016)

Interleukin-4 Stimulates Proliferation and Growth of T-Cell Acute Lymphoblastic Leukemia Cells by Activating mTOR Signaling

Por Cardoso, Bruno A., Martins, Leila R., Santos, Cristina, Nadler, Lee M., Boussiotis, Vassiliki A., Cardoso, Angelo A., Barata, Joao T.
Publicado em 2008

Ref-1/APE1 as Transcriptional Regulator and Novel Therapeutic Target in Pediatric T-cell Leukemia

Por Ding, Jixin, Fishel, Melissa L., Reed, April M., McAdams, Erin, Czader, Magdalena, Cardoso, Angelo A., Kelley, Mark R.
Publicado no Mol Cancer Ther (2017)

Aberrant Expression of Functional BAFF-System Receptors by Malignant B-Cell Precursors Impacts Leukemia Cell Survival

Por Maia, Sara, Pelletier, Marc, Ding, Jixin, Hsu, Yen-Ming, Sallan, Stephen E., Rao, Sambasiva P., Nadler, Lee M., Cardoso, Angelo A.
Publicado em 2011

Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence

Por Yoshimoto, Momoko, Porayette, Prashanth, Glosson, Nicole L., Conway, Simon J., Carlesso, Nadia, Cardoso, Angelo A., Kaplan, Mark H., Yoder, Mervin C.
Publicado em 2012

APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1–STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival

Por Cardoso, Angelo A., Jiang, Yanlin, Luo, Meihua, Reed, April M., Shahda, Safi, He, Ying, Maitra, Anirban, Kelley, Mark R., Fishel, Melissa L.
Publicado em 2012

Phosphatase PRL2 promotes oncogenic NOTCH1-induced T cell leukemia

Por Kobayashi, Michihiro, Bai, Yunpeng, Chen, Sisi, Gao, Rui, Yao, Chonghua, Cai, Wenjing, Cardoso, Angelo A., Croop, James, Zhang, Zhong-Yin, Liu, Yan
Publicado no Leukemia (2016)

Notch1 modulates timing of G(1)-S progression by inducing SKP2 transcription and p27(Kip1) degradation

Por Sarmento, Leonor M., Huang, Hui, Limon, Ana, Gordon, William, Fernandes, Jacquenilson, Tavares, Maria J., Miele, Lucio, Cardoso, Angelo A., Classon, Marie, Carlesso, Nadia
Publicado em 2005

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

Por Silva, Ana, Yunes, J. Andrés, Cardoso, Bruno A., Martins, Leila R., Jotta, Patrícia Y., Abecasis, Miguel, Nowill, Alexandre E., Leslie, Nick R., Cardoso, Angelo A., Barata, Joao T.
Publicado em 2008

TNFα and Endothelial Cells Modulate Notch Signaling in the Bone Marrow Microenvironment during Inflammation

Por Fernandez, Luis, Rodriguez, Sonia, Huang, Hui, Chora, Angelo, Mumaw, Christin, Cruz, Eugenia, Pollok, Karen, Cristina, Filipa, Price, Joanne E., Ferkowicz, Michael J., Scadden, David T., Clauss, Matthias, Cardoso, Angelo A., Carlesso, Nadia
Publicado em 2008

Cell adhesion molecule CD166 drives malignant progression and osteolytic disease in multiple myeloma

Por Xu, Linlin, Mohammad, Khalid S., Wu, Hao, Crean, Colin, Poteat, Bradley, Cheng, Yinghua, Cardoso, Angelo A., Machal, Christophe, Hanenberg, Helmut, Abonour, Rafat, Kacena, Melissa A., Chirgwin, John, Suvannasankha, Attaya, Srour, Edward F.
Publicado no Cancer Res (2016)

A non-canonical Flt3ITD/NF-κB signaling pathway represses DAPK1 in acute myeloid leukemia (AML)

Por Shanmugam, Rajasubramaniam, Gade, Padmaja, Wilson-Weekes, Annique, Sayar, Hamid, Suvannasankha, Attaya, Goswami, Chirayu, Li, Lang, Gupta, Sushil, Cardoso, Angelo A., Baghdadi, Tareq Al, Sargent, Katie J., Cripe, Larry D., Kalvakolanu, Dhananjaya V., Boswell, H. Scott
Publicado em 2011

CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche

Por Chitteti, Brahmananda Reddy, Kobayashi, Michihiro, Cheng, Yinghua, Zhang, Huajia, Poteat, Bradley A., Broxmeyer, Hal E., Pelus, Louis M., Hanenberg, Helmut, Zollman, Amy, Kamocka, Malgorzata M., Carlesso, Nadia, Cardoso, Angelo A., Kacena, Melissa A., Srour, Edward F.
Publicado em 2014

Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB dependent manner

Por Wang, Lin, Zhang, Huajia, Rodriguez, Sonia, Cao, Liyun, Parish, Jonathan, Mumaw, Christen, Zollman, Amy, Kamocka, Gosia, Mu, Jian, Chen, Danny Z., Srour, Edward F., Chitteti, Brahmananda R., HogenEsch, Harm, Tu, Xiaolin, Bellido, Teresita M., Boswell, Scott, Manshouri, Taghi, Verstovsek, Srdan, Yoder, Mervin C., Kapur, Reuben, Cardoso, Angelo A., Carlesso, Nadia
Publicado no Cell Stem Cell (2014)