A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts a less severe expression of hereditary hemochromatosis

Por Cruz, Eugénia, Whittington, Chris, Krikler, Samuel H, Mascarenhas, Cláudia, Lacerda, Rosa, Vieira, Jorge, Porto, Graça
Publicado em 2008

A study of 82 extended HLA haplotypes in HFE-C282Y homozygous hemochromatosis subjects: relationship to the genetic control of CD8+ T-lymphocyte numbers and severity of iron overlo...

Por Cruz, Eugénia, Vieira, Jorge, Almeida, Susana, Lacerda, Rosa, Gartner, Andrea, Cardoso, Carla S, Alves, Helena, Porto, Graça
Publicado em 2006

Effects of Highly Conserved Major Histocompatibility Complex (MHC) Extended Haplotypes on Iron and Low CD8(+) T Lymphocyte Phenotypes in HFE C282Y Homozygous Hemochromatosis Patien...

Por Costa, Mónica, Cruz, Eugénia, Barton, James C., Thorstensen, Ketil, Morais, Sandra, da Silva, Berta M., Pinto, Jorge P., Vieira, Cristina P., Vieira, Jorge, Acton, Ronald T., Porto, Graça
Publicado em 2013

TNFα and Endothelial Cells Modulate Notch Signaling in the Bone Marrow Microenvironment during Inflammation

Por Fernandez, Luis, Rodriguez, Sonia, Huang, Hui, Chora, Angelo, Mumaw, Christin, Cruz, Eugenia, Pollok, Karen, Cristina, Filipa, Price, Joanne E., Ferkowicz, Michael J., Scadden, David T., Clauss, Matthias, Cardoso, Angelo A., Carlesso, Nadia
Publicado em 2008

Lymphocyte Gene Expression Signatures from Patients and Mouse Models of Hereditary Hemochromatosis Reveal a Function of HFE as a Negative Regulator of CD8(+) T-Lymphocyte Activatio...

Por Costa, Mónica, Cruz, Eugénia, Oliveira, Susana, Benes, Vladimir, Ivacevic, Tomi, Silva, Maria João, Vieira, Inês, Dias, Francisco, Fonseca, Sónia, Gonçalves, Marta, Lima, Margarida, Leitão, Catarina, Muckenthaler, Martina U., Pinto, Jorge, Porto, Graça
Publicado no PLoS One (2015)