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A study of 82 extended HLA haplotypes in HFE-C282Y homozygous hemochromatosis subjects: relationship to the genetic control of CD8+ T-lymphocyte numbers and severity of iron overload

BACKGROUND: It has been recently demonstrated that CD8+ T-lymphocyte numbers are genetically transmitted in association with the MHC class I region. The present study was designed with the objective of narrowing the region associated with the setting of CD8+ T-lymphocyte numbers in a population of C...

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Detalhes bibliográficos
Main Authors: Cruz, Eugénia, Vieira, Jorge, Almeida, Susana, Lacerda, Rosa, Gartner, Andrea, Cardoso, Carla S, Alves, Helena, Porto, Graça
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413516/
https://ncbi.nlm.nih.gov/pubmed/16509978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-7-16
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