Survivin mediates aberrant hematopoietic progenitor cell proliferation and acute leukemia in mice induced by internal tandem duplication of Flt3

Por Fukuda, Seiji, Singh, Pratibha, Moh, Akira, Abe, Mariko, Conway, Edward M., Boswell, H. Scott, Yamaguchi, Seiji, Fu, Xin-Yuan, Pelus, Louis M.
Publicado em 2009

Death-associated Protein Kinase-1 Expression and Autophagy in Chronic Lymphocytic Leukemia Are Dependent on Activating Transcription Factor-6 and CCAAT/Enhancer-binding Protein-β

Por Gade, Padmaja, Kimball, Amy S., DiNardo, Angela C., Gangwal, Priyamvada, Ross, Douglas D., Boswell, H. Scott, Keay, Susan K., Kalvakolanu, Dhananjaya V.
Publicado no J Biol Chem (2016)

Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53

Por Chen, Sisi, Gao, Rui, Yao, Chonghua, Kobayashi, Michihiro, Liu, Stephen Z., Yoder, Mervin C., Broxmeyer, Hal, Kapur, Reuben, Boswell, H. Scott, Mayo, Lindsey D., Liu, Yan
Publicado no Leukemia (2017)

DPP4 Truncated GM-CSF & IL-3 Manifest Distinct Receptor Binding & Regulatory Functions Compared to their Full Length Forms

Por O’Leary, Heather Ann, Capitano, Maegan, Cooper, Scott, Mantel, Charlie, Boswell, H. Scott, Kapur, Reuben, Ramdas, Baskar, Chan, Rebecca, Deng, Lisa, Qu, Cheng-Kui, Broxmeyer, Hal E.
Publicado no Leukemia (2017)

Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia

Por Richine, Briana M., Virts, Elizabeth L., Bowling, Joshua D., Ramdas, Baskar, Mali, Raghu, Naoye, Ruben, Liu, Ziyue, Zhang, Zhong-Yin, Boswell, H. Scott, Kapur, Reuben, Chan, Rebecca J.
Publicado no Leukemia (2016)

A non-canonical Flt3ITD/NF-κB signaling pathway represses DAPK1 in acute myeloid leukemia (AML)

Por Shanmugam, Rajasubramaniam, Gade, Padmaja, Wilson-Weekes, Annique, Sayar, Hamid, Suvannasankha, Attaya, Goswami, Chirayu, Li, Lang, Gupta, Sushil, Cardoso, Angelo A., Baghdadi, Tareq Al, Sargent, Katie J., Cripe, Larry D., Kalvakolanu, Dhananjaya V., Boswell, H. Scott
Publicado em 2011

Phosphatase PRL2 promotes AML1-ETO-induced acute myeloid leukemia

Por Kobayashi, Michihiro, Chen, Sisi, Bai, Yunpeng, Yao, Chonghua, Gao, Rui, Sun, Xiao-Jian, Mu, Chen, Twiggs, Taylor A., Yu, Zhi-Hong, Boswell, H. Scott, Yoder, Mervin C., Kapur, Reuben, Mulloy, James C., Zhang, Zhong-Yin, Liu, Yan
Publicado no Leukemia (2017)

Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML

Por Sayar, Hamid, Liu, Yan, Gao, Rui, Zaid, Mohammad Abu, Cripe, Larry D., Weisenbach, Jill, Sargent, Katie J., Nassiri, Mehdi, Li, Lang, Konig, Heiko, Suvannasankha, Attaya, Pan, Feng, Shanmugam, Rajasubramaniam, Goswami, Chirayu, Kapur, Reuben, Xu, Mingjiang, Boswell, H. Scott
Publicado no Oncotarget (2017)

The Protein Tyrosine Phosphatase, Shp2, Positively Contributes to FLT3-ITD-Induced Hematopoietic Progenitor Hyperproliferation and Malignant Disease In Vivo

Por Nabinger, Sarah C., Li, XingJun, Ramdas, Baskar, He, Yantao, Zhang, Xian, Zeng, Lifan, Richine, Briana, Bowling, Joshua D., Fukuda, Seiji, Goenka, Shreevrat, Liu, Ziyue, Feng, Gen-Sheng, Yu, Menggang, Sandusky, George E., Boswell, H. Scott, Zhang, Zhong-Yin, Kapur, Reuben, Chan, Rebecca J.
Publicado em 2012

Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3 and KIT driven Leukemogenesis

Por Chatterjee, Anindya, Ghosh, Joydeep, Ramdas, Baskar, Mali, Raghuveer Singh, Martin, Holly, Kobayashi, Michihiro, Vemula, Sasidhar, Canela, Victor H., Waskow, Emily R., Visconte, Valeria, Tiu, Ramon V., Smith, Catherine C., Shah, Neil, Bunting, Kevin D., Boswell, H. Scott, Liu, Yan, Chan, Rebecca J., Kapur, Reuben
Publicado no Cell Rep (2014)

Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3 and BCR-ABL

Por Mali, Raghuveer Singh, Ramdas, Baskar, Ma, Peilin, Shi, Jianjian, Munugalavadla, Veerendra, Sims, Emily, Wei, Lei, Vemula, Sasidhar, Nabinger, Sarah C., Goodwin, Charles B., Chan, Rebecca J., Traina, Fabiola, Visconte, Valeria, Tiu, Ramon V., Lewis, Timothy A., Stern, Andrew M., Wen, Qiang, Crispino, John D., Boswell, H. Scott, Kapur, Reuben
Publicado em 2011