Directing p53 to induce autophagy

Por Mayo, Lindsey D.
Publicado em 2012

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

Por Mayo, Lindsey D., Donner, David B.
Publicado em 2001

Integration of DNA Damage and Repair with Murine Double-Minute 2 (Mdm2) in Tumorigenesis

Por Lehman, Jason A., Mayo, Lindsey D.
Publicado em 2012

Emerging Non-Canonical Functions and Regulation by p53: p53 and Stemness

Por Olivos, David J., Mayo, Lindsey D.
Publicado no Int J Mol Sci (2016)

Therapeutic considerations for Mdm2: not just a one trick pony

Por Lehman, Jason A., Eitel, Jacob A., Batuello, Christopher N., Mayo, Lindsey D.
Publicado em 2008

Up-Regulation of Hepatitis C Virus Replication and Production by Inhibition of MEK/ERK Signaling

Por Ndjomou, Jean, Park, In-woo, Liu, Ying, Mayo, Lindsey D., He, Johnny J.
Publicado em 2009

Controlling the Mdm2-Mdmx-p53 Circuit

Por Waning, David L., Lehman, Jason A., Batuello, Christopher N., Mayo, Lindsey D.
Publicado em 2010

c-Abl Phosphorylation of Mdm2 Facilitates Mdm2-Mdmx Complex Formation

Por Waning, David L., Lehman, Jason A., Batuello, Christopher N., Mayo, Lindsey D.
Publicado em 2011

Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain

Por Yadavilli, Sridevi, Mayo, Lindsey D., Higgins, Maureen, Lain, Sonia, Hegde, Vijay, Deutsch, Walter A.
Publicado em 2009

Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth

Por Zhang, YiWei, Zhang, Qi, Zeng, Shelya X., Zhang, Yu, Mayo, Lindsey D., Lu, Hua
Publicado em 2012

Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase

Por Batuello, Christopher N., Hauck, Paula M., Gendron, Jaimie M., Lehman, Jason A., Mayo, Lindsey D.
Publicado no Proc Natl Acad Sci U S A (2015)

Induction of Apoptotic Genes by a p73-Phosphatase and Tensin Homolog (p73-PTEN) Protein Complex in Response to Genotoxic Stress

Por Lehman, Jason A., Waning, David L., Batuello, Christopher N., Cipriano, Rocky, Kadakia, Madhavi P., Mayo, Lindsey D.
Publicado em 2011

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1

Por Ozes, Osman Nidai, Akca, Hakan, Mayo, Lindsey D., Gustin, Jason A., Maehama, Tomohiko, Dixon, Jack E., Donner, David B.
Publicado em 2001

Megakaryocytes Regulate Expression of Pyk2 Isoforms and Caspase-mediated Cleavage of Actin in Osteoblasts

Por Kacena, Melissa A., Eleniste, Pierre P., Cheng, Ying-Hua, Huang, Su, Shivanna, Mahesh, Meijome, Tomas E., Mayo, Lindsey D., Bruzzaniti, Angela
Publicado em 2012

Hdm2 is an Ubiquitin Ligase of Ku70 -Akt Promotes Cell Survival by Inhibiting Hdm2-dependent Ku70 Destabilization

Por Gama, Vivian, Gomez, Jose A., Mayo, Lindsey D., Jackson, Mark W., Danielpour, David, Song, Kyung, Haas, Arthur L., Laughlin, Mary J., Matsuyama, Shigemi
Publicado em 2009

Serdemetan Antagonizes the Mdm2-HIF1α Axis Leading to Decreased Levels of Glycolytic Enzymes

Por Lehman, Jason A., Hauck, Paula M., Gendron, Jaimie M., Batuello, Christopher N., Eitel, Jacob A., Albig, Allan, Kadakia, Madhavi P., Mayo, Lindsey D.
Publicado em 2013

TGF-β1–induced expression of human Mdm2 correlates with late-stage metastatic breast cancer

Por Araki, Shinako, Eitel, Jacob A., Batuello, Christopher N., Bijangi-Vishehsaraei, Khadijeh, Xie, Xian-Jin, Danielpour, David, Pollok, Karen E., Boothman, David A., Mayo, Lindsey D.
Publicado em 2009

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma

Por Lakhter, Alexander J., Hamilton, James, Dagher, Pierre C., Mukkamala, Suresh, Hato, Takashi, Dong, X. Charlie, Mayo, Lindsey D., Harris, Robert A., Shekhar, Anantha, Ivan, Mircea, Brustovetsky, Nickolay, Naidu, Samisubbu R.
Publicado no Oncotarget (2014)

Humanized bone-marrow mouse model as a pre-clinical tool to assess therapy-mediated hematotoxicity

Por Cai, Shanbao, Wang, Haiyan, Bailey, Barbara, Ernstberger, Aaron, Juliar, Beth E., Sinn, Anthony L., Chan, Rebecca J., Jones, David R., Mayo, Lindsey D., Baluyut, Arthur R., Goebel, W. Scott, Pollok, Karen E.
Publicado em 2011

Signaling pathways involved in megakaryocyte-mediated proliferation of osteoblast lineage cells

Por Cheng, Ying-Hua, Streicher, Drew A., Waning, David L., Chitteti, Brahmananda R., Gerard-O’Riley, Rita, Horowitz, Mark C., Bidwell, Joseph P., Pavalko, Fredrick M., Srour, Edward F., Mayo, Lindsey D., Kacena, Melissa A.
Publicado no J Cell Physiol (2015)