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Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth

Several proteins have been suggested in promoting tumor formation in numerous human tissues by inactivating the tumor suppressor p53. This has generated interest in the development of small molecules to block these inhibitors of p53 and to regain p53 activity. Recently, we identified a small molecul...

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Bibliographic Details
Main Authors: Zhang, YiWei, Zhang, Qi, Zeng, Shelya X., Zhang, Yu, Mayo, Lindsey D., Lu, Hua
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414413/
https://ncbi.nlm.nih.gov/pubmed/22785205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20844
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