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Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth

Several proteins have been suggested in promoting tumor formation in numerous human tissues by inactivating the tumor suppressor p53. This has generated interest in the development of small molecules to block these inhibitors of p53 and to regain p53 activity. Recently, we identified a small molecul...

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Detalhes bibliográficos
Main Authors: Zhang, YiWei, Zhang, Qi, Zeng, Shelya X., Zhang, Yu, Mayo, Lindsey D., Lu, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414413/
https://ncbi.nlm.nih.gov/pubmed/22785205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20844
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