Structure and Activity Analysis of Inauhzin Analogs as Novel Antitumor Compounds That Induce p53 and Inhibit Cell Growth

Identifying effective small molecules that specifically target the p53 pathway in cancer has been an exciting, though challenging, approach for the development of anti-cancer therapy. We recently identified Inauhzin (INZ) as a novel p53 activator, selectively and efficiently suppressing tumor growth...

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Bibliographic Details
Main Authors: Zhang, Qi, Ding, Derong, Zeng, Shelya X., Ye, Qi-Zhuang, Lu, Hua
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480348/
https://ncbi.nlm.nih.gov/pubmed/23115626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046294
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