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Determination of maximum tolerated dose and toxicity of Inauhzin in mice

Reactivating the tumor suppressor p53 offers an attractive strategy for developing cancer therapy. We recently identified Inauhzin (INZ) as a novel non-genotoxic p53-activating compound. To develop INZ into a clinically applicable anticancer drug, we have initiated preclinical toxicity studies. Here...

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Enregistré dans:
Détails bibliographiques
Publié dans:Toxicol Rep
Auteurs principaux: Zhang, Qi, Zeng, Shelya X., Lu, Hua
Format: Artigo
Langue:Inglês
Publié: Elsevier 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497815/
https://ncbi.nlm.nih.gov/pubmed/26167454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.02.011
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