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Integration of DNA Damage and Repair with Murine Double-Minute 2 (Mdm2) in Tumorigenesis

The alteration of tumorigenic pathways leading to cancer is a degenerative disease process typically involving inactivation of tumor suppressor proteins and hyperactivation of oncogenes. One such oncogenic protein product is the murine double-minute 2, or Mdm2. While, Mdm2 has been primarily associa...

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Bibliografske podrobnosti
Main Authors: Lehman, Jason A., Mayo, Lindsey D.
Format: Artigo
Jezik:Inglês
Izdano: Molecular Diversity Preservation International (MDPI) 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546695/
https://ncbi.nlm.nih.gov/pubmed/23208375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131216373
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