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Notch1 modulates timing of G(1)-S progression by inducing SKP2 transcription and p27(Kip1) degradation
Cyclin-dependent kinase inhibitors (CKIs) and Notch receptor activation have been shown to influence adult stem cells and progenitors by altering stem cell self-renewal and proliferation. Yet, no interaction between these molecular pathways has been defined. Here we show that ligand-independent and...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212905/ https://ncbi.nlm.nih.gov/pubmed/15998794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050559 |
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