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The Amelioration of Renal Damage in Skp2-Deficient Mice Canceled by p27 (Kip1) Deficiency in Skp2(−/−) p27(−/−) Mice
SCF-Skp2 E3 ubiquitin ligase (Skp2 hereafter) targets several cell cycle regulatory proteins for degradation via the ubiquitin-dependent pathway. However, the target-specific physiological functions of Skp2 have not been fully elucidated in kidney diseases. We previously reported an increase in Skp2...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338689/ https://ncbi.nlm.nih.gov/pubmed/22558406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036249 |
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