Skp2 Deficiency Inhibits Chemical Skin Tumorigenesis Independent of p27(Kip1) Accumulation

S-phase kinase-associated protein 2 (Skp2) functions as the receptor component of the Skp–Cullin–F-box complex and is implicated in the degradation of several cell cycle regulators, such as p21(Cip1), p27(Kip1), p57(Kip2), and cyclin E. Numerous studies in human and experimental tumors have demonstr...

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Detaylı Bibliyografya
Asıl Yazarlar: Sistrunk, Christopher, Kim, Sun Hye, Wang, Xian, Lee, Sung Hyun, Kim, Yongbaek, Macias, Everardo, Rodriguez-Puebla, Marcelo L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2013
Konular:
Regular Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644727/
https://ncbi.nlm.nih.gov/pubmed/23474082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.01.016
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