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Combined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor development

We have previously demonstrated that ras-mediated skin tumorigenesis depends on signaling pathways that act preferentially through cyclin D1 and D2. Interestingly, the expression of cyclin D3 inhibits skin tumor development, an observation that conflicts with the oncogenic role of D-type cyclins in...

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Bibliografische gegevens
Hoofdauteurs: Wang, Xian, Sistrunk, Christopher, Miliani de Marval, Paula L, Kim, Yongbaek, Rodriguez-Puebla, Marcelo L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293382/
https://ncbi.nlm.nih.gov/pubmed/22214766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.2.18774
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