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Cyclin D3 deficiency inhibits skin tumor development, but does not affect normal keratinocyte proliferation

Rearrangement and amplification of the D-type cyclin genes have been reported in human cancer. Previous studies have demonstrated that Ras-mediated skin tumorigenesis depends on pathways that act through cyclin D1 and D2; however, the role of cyclin D3 remains unknown. The present study demonstrates...

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Podrobná bibliografie
Vydáno v:Oncol Lett
Hlavní autoři: Lee, Sung Hyun, Wang, Xian, Kim, Sun Hye, Kim, Yongbaek, Rodriguez-Puebla, Marcelo L.
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588102/
https://ncbi.nlm.nih.gov/pubmed/28927034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6551
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