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Combined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor development

We have previously demonstrated that ras-mediated skin tumorigenesis depends on signaling pathways that act preferentially through cyclin D1 and D2. Interestingly, the expression of cyclin D3 inhibits skin tumor development, an observation that conflicts with the oncogenic role of D-type cyclins in...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Xian, Sistrunk, Christopher, Miliani de Marval, Paula L, Kim, Yongbaek, Rodriguez-Puebla, Marcelo L
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293382/
https://ncbi.nlm.nih.gov/pubmed/22214766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.2.18774
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