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Combined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor development
We have previously demonstrated that ras-mediated skin tumorigenesis depends on signaling pathways that act preferentially through cyclin D1 and D2. Interestingly, the expression of cyclin D3 inhibits skin tumor development, an observation that conflicts with the oncogenic role of D-type cyclins in...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Landes Bioscience
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293382/ https://ncbi.nlm.nih.gov/pubmed/22214766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.2.18774 |
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