Notch1 modulates timing of G(1)-S progression by inducing SKP2 transcription and p27(Kip1) degradation

Cyclin-dependent kinase inhibitors (CKIs) and Notch receptor activation have been shown to influence adult stem cells and progenitors by altering stem cell self-renewal and proliferation. Yet, no interaction between these molecular pathways has been defined. Here we show that ligand-independent and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sarmento, Leonor M., Huang, Hui, Limon, Ana, Gordon, William, Fernandes, Jacquenilson, Tavares, Maria J., Miele, Lucio, Cardoso, Angelo A., Classon, Marie, Carlesso, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212905/
https://ncbi.nlm.nih.gov/pubmed/15998794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050559
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados