Carregant...
Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL
Timed degradation of the cyclin-dependent kinase inhibitor p27(Kip1) by the E3 ubiquitin ligase F-box protein SKP2 is critical for T-cell progression into cell cycle, coordinating proliferation and differentiation processes. SKP2 expression is regulated by mitogenic stimuli and by Notch signaling, a...
Guardat en:
| Publicat a: | Leukemia |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7192844/ https://ncbi.nlm.nih.gov/pubmed/31772299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0653-z |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|