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Emerging roles for the FBXW7 ubiquitin ligase in leukemia and beyond
Protein degradation plays key roles in diverse pathways in cell division, growth and differentiation. Aberrant stabilization of crucial proteins participating in oncogenic pathways is often observed in cancer. The importance of proper protein turnover is exemplified by the SCF(Fbxw7) ubiquitin ligas...
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| 出版年: | Curr Opin Cell Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687017/ https://ncbi.nlm.nih.gov/pubmed/26426760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2015.09.003 |
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