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Emerging roles for the FBXW7 ubiquitin ligase in leukemia and beyond
Protein degradation plays key roles in diverse pathways in cell division, growth and differentiation. Aberrant stabilization of crucial proteins participating in oncogenic pathways is often observed in cancer. The importance of proper protein turnover is exemplified by the SCF(Fbxw7) ubiquitin ligas...
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| Udgivet i: | Curr Opin Cell Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687017/ https://ncbi.nlm.nih.gov/pubmed/26426760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2015.09.003 |
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