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Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

Estrogen receptor (ER) expression and Her-2 amplification define specific subsets of breast tumors for which specific therapies exist. The S-phase kinase-associated protein Skp2 is required for the ubiquitin-mediated degradation of the cdk-inhibitor p27 and is a bona fide proto-oncoprotein. Using mi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Signoretti, Sabina, Di Marcotullio, Lucia, Richardson, Andrea, Ramaswamy, Sridhar, Isaac, Beth, Rue, Montserrat, Monti, Franco, Loda, Massimo, Pagano, Michele
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC151109/
https://ncbi.nlm.nih.gov/pubmed/12208864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15795
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