Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone

Osteocytes, >90% of the cells in bone, lie embedded within the mineralized matrix and coordinate osteoclast and osteoblast activity on bone surfaces by mechanisms still unclear. Bone anabolic stimuli activate Wnt signaling, and human mutations of components along this pathway underscore its cruci...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tu, Xiaolin, Delgado-Calle, Jesus, Condon, Keith W., Maycas, Marta, Zhang, Huajia, Carlesso, Nadia, Taketo, Makoto M., Burr, David B., Plotkin, Lilian I., Bellido, Teresita
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321271/
https://ncbi.nlm.nih.gov/pubmed/25605937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409857112
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