Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone

Osteocytes, >90% of the cells in bone, lie embedded within the mineralized matrix and coordinate osteoclast and osteoblast activity on bone surfaces by mechanisms still unclear. Bone anabolic stimuli activate Wnt signaling, and human mutations of components along this pathway underscore its cruci...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Tu, Xiaolin, Delgado-Calle, Jesus, Condon, Keith W., Maycas, Marta, Zhang, Huajia, Carlesso, Nadia, Taketo, Makoto M., Burr, David B., Plotkin, Lilian I., Bellido, Teresita
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321271/
https://ncbi.nlm.nih.gov/pubmed/25605937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409857112
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