Loading...

Inhibition of Osteocyte Apoptosis Prevents the Increase in Osteocytic Receptor Activator of Nuclear Factor κB Ligand (RANKL) but Does Not Stop Bone Resorption or the Loss of Bone Induced by Unloading

Apoptosis of osteocytes and osteoblasts precedes bone resorption and bone loss with reduced mechanical stimulation, and receptor activator of NF-κB ligand (RANKL) expression is increased with unloading in mice. Because osteocytes are major RANKL producers, we hypothesized that apoptotic osteocytes s...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Plotkin, Lilian I., Gortazar, Arancha R., Davis, Hannah M., Condon, Keith W., Gabilondo, Hugo, Maycas, Marta, Allen, Matthew R., Bellido, Teresita
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521013/
https://ncbi.nlm.nih.gov/pubmed/26085098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642090
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!