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Parathyroid Hormone Receptor Signaling Induces Bone Resorption in the Adult Skeleton by Directly Regulating the RANKL Gene in Osteocytes

PTH upregulates the expression of the receptor activator of nuclear factor κB ligand (Rankl) in cells of the osteoblastic lineage, but the precise differentiation stage of the PTH target cell responsible for RANKL-mediated stimulation of bone resorption remains undefined. We report that constitutive...

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Autors principals: Ben-awadh, Abdullah N., Delgado-Calle, Jesus, Tu, Xiaolin, Kuhlenschmidt, Kali, Allen, Matthew R., Plotkin, Lilian I., Bellido, Teresita
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098003/
https://ncbi.nlm.nih.gov/pubmed/24877630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1046
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