MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production

Parathyroid hormone (PTH) affects the skeleton by acting on osteocytes (Ots) in bone through yet unclear mechanisms. We report that matrix metalloproteinase 14 (MMP14) expression/activity are increased in bones from mice with genetic constitutive activation (ca) of the PTH receptor 1 (PTH1R) in Ots...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:FASEB J
Main Authors: Delgado-Calle, Jesus, Hancock, Benjamin, Likine, Elive F., Sato, Amy Y., McAndrews, Kevin, Sanudo, Carolina, Bruzzaniti, Angela, Riancho, Jose A., Tonra, James R., Bellido, Teresita
פורמט: Artigo
שפה:Inglês
יצא לאור: Federation of American Societies for Experimental Biology 2018
נושאים:
Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901377/
https://ncbi.nlm.nih.gov/pubmed/29401593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700919RRR
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