Parathyroid Hormone Receptor Signaling Induces Bone Resorption in the Adult Skeleton by Directly Regulating the RANKL Gene in Osteocytes

PTH upregulates the expression of the receptor activator of nuclear factor κB ligand (Rankl) in cells of the osteoblastic lineage, but the precise differentiation stage of the PTH target cell responsible for RANKL-mediated stimulation of bone resorption remains undefined. We report that constitutive...

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Bibliografiset tiedot
Päätekijät: Ben-awadh, Abdullah N., Delgado-Calle, Jesus, Tu, Xiaolin, Kuhlenschmidt, Kali, Allen, Matthew R., Plotkin, Lilian I., Bellido, Teresita
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Endocrine Society 2014
Aiheet:
Calcium-Regulating Hormones
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098003/
https://ncbi.nlm.nih.gov/pubmed/24877630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1046
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