Anti–PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma

BACKGROUND: Most glioblastomas recur near prior radiation treatment sites. Future clinical success will require achieving and optimizing an “abscopal effect,” whereby unirradiated neoplastic cells outside treatment sites are recognized and attacked by the immune system. Radiation combined with anti–...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Ene, Chibawanye I, Kreuser, Shannon A, Jung, Miyeon, Zhang, Huajia, Arora, Sonali, White Moyes, Kara, Szulzewsky, Frank, Barber, Jason, Cimino, Patrick J, Wirsching, Hans-Georg, Patel, Anoop, Kong, Paul, Woodiwiss, Timothy R, Durfy, Sharon J, Houghton, A McGarry, Pierce, Robert H, Parney, Ian F, Crane, Courtney A, Holland, Eric C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229244/
https://ncbi.nlm.nih.gov/pubmed/31793634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz226
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