Anti–PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma

BACKGROUND: Most glioblastomas recur near prior radiation treatment sites. Future clinical success will require achieving and optimizing an “abscopal effect,” whereby unirradiated neoplastic cells outside treatment sites are recognized and attacked by the immune system. Radiation combined with anti–...

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Enregistré dans:
Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Ene, Chibawanye I, Kreuser, Shannon A, Jung, Miyeon, Zhang, Huajia, Arora, Sonali, White Moyes, Kara, Szulzewsky, Frank, Barber, Jason, Cimino, Patrick J, Wirsching, Hans-Georg, Patel, Anoop, Kong, Paul, Woodiwiss, Timothy R, Durfy, Sharon J, Houghton, A McGarry, Pierce, Robert H, Parney, Ian F, Crane, Courtney A, Holland, Eric C
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Basic and Translational Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229244/
https://ncbi.nlm.nih.gov/pubmed/31793634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz226
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