Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury

Por Zou, Wei, Roth, Robert A., Younis, Husam S., Malle, Ernst, Ganey, Patricia E.
Publicado em 2011

Oxidative stress is important in the pathogenesis of liver injury induced by sulindac and lipopolysaccharide cotreatment

Por Zou, Wei, Roth, Robert A., Younis, Husam S., Burgoon, Lyle D., Ganey, Patricia E.
Publicado em 2010

Hepatotoxic Interaction of Sulindac with Lipopolysaccharide: Role of the Hemostatic System

Por Zou, Wei, Devi, Sachin S., Sparkenbaugh, Erica, Younis, Husam S., Roth, Robert A., Ganey, Patricia E.
Publicado em 2009

Sulindac Metabolism and Synergy with Tumor Necrosis Factor-α in a Drug-Inflammation Interaction Model of Idiosyncratic Liver Injury

Por Zou, Wei, Beggs, Kevin M., Sparkenbaugh, Erica M., Jones, A. Daniel, Younis, Husam S., Roth, Robert A., Ganey, Patricia E.
Publicado em 2009

Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers

Por Crooke, Stanley T, Baker, Brenda F, Kwoh, T Jesse, Cheng, Wei, Schulz, Dan J, Xia, Shuting, Salgado, Nelson, Bui, Huynh-Hoa, Hart, Christopher E, Burel, Sebastien A, Younis, Husam S, Geary, Richard S, Henry, Scott P, Bhanot, Sanjay
Publicado no Mol Ther (2016)

Identification and Characterization of Modified Antisense Oligonucleotides Targeting DMPK in Mice and Nonhuman Primates for the Treatment of Myotonic Dystrophy Type 1

Por Pandey, Sanjay K., Wheeler, Thurman M., Justice, Samantha L., Kim, Aneeza, Younis, Husam S., Gattis, Danielle, Jauvin, Dominic, Puymirat, Jack, Swayze, Eric E., Freier, Susan M., Bennett, C. Frank, Thornton, Charles A., MacLeod, A. Robert
Publicado no J Pharmacol Exp Ther (2015)

Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts

Por Burel, Sebastien A., Hart, Christopher E., Cauntay, Patrick, Hsiao, Jill, Machemer, Todd, Katz, Melanie, Watt, Andy, Bui, Huynh-hoa, Younis, Husam, Sabripour, Mahyar, Freier, Susan M., Hung, Gene, Dan, Amy, Prakash, T.P., Seth, Punit P., Swayze, Eric E., Bennett, C. Frank, Crooke, Stanley T., Henry, Scott P.
Publicado no Nucleic Acids Res (2016)