Dichotomy of AML1-ETO Functions: Growth Arrest versus Block of Differentiation

Por Burel, Sebastien A., Harakawa, Nari, Zhou, Liming, Pabst, Thomas, Tenen, Daniel G., Zhang, Dong-Er
Publicado em 2001

Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development

Por Yan, Ming, Burel, Sebastien A., Peterson, Luke F., Kanbe, Eiki, Iwasaki, Hiromi, Boyapati, Anita, Hines, Robert, Akashi, Koichi, Zhang, Dong-Er
Publicado em 2004

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

Por Yuan, Youzhong, Zhou, Liming, Miyamoto, Toshihiro, Iwasaki, Hiromi, Harakawa, Nari, Hetherington, Christopher J., Burel, Sebastien A., Lagasse, Eric, Weissman, Irving L., Akashi, Koichi, Zhang, Dong-Er
Publicado em 2001

Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers

Por Crooke, Stanley T, Baker, Brenda F, Kwoh, T Jesse, Cheng, Wei, Schulz, Dan J, Xia, Shuting, Salgado, Nelson, Bui, Huynh-Hoa, Hart, Christopher E, Burel, Sebastien A, Younis, Husam S, Geary, Richard S, Henry, Scott P, Bhanot, Sanjay
Publicado no Mol Ther (2016)

Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts

Por Burel, Sebastien A., Hart, Christopher E., Cauntay, Patrick, Hsiao, Jill, Machemer, Todd, Katz, Melanie, Watt, Andy, Bui, Huynh-hoa, Younis, Husam, Sabripour, Mahyar, Freier, Susan M., Hung, Gene, Dan, Amy, Prakash, T.P., Seth, Punit P., Swayze, Eric E., Bennett, C. Frank, Crooke, Stanley T., Henry, Scott P.
Publicado no Nucleic Acids Res (2016)