Dichotomy of AML1-ETO Functions: Growth Arrest versus Block of Differentiation

The fusion gene AML1-ETO is the product of t(8;21)(q22;q22), one of the most common chromosomal translocations associated with acute myeloid leukemia. To investigate the impact of AML1-ETO on hematopoiesis, tetracycline-inducible AML1-ETO-expressing cell lines were generated using myeloid cells. AML...

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Detalhes bibliográficos
Main Authors: Burel, Sebastien A., Harakawa, Nari, Zhou, Liming, Pabst, Thomas, Tenen, Daniel G., Zhang, Dong-Er
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87279/
https://ncbi.nlm.nih.gov/pubmed/11463839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5577-5590.2001
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