The t(8;21) Fusion Product, AML-1–ETO, Associates with C/EBP-α, Inhibits C/EBP-α-Dependent Transcription, and Blocks Granulocytic Differentiation

Eitemau Tebyg

• The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation.
  gan: Meyers, S, et al.
  Cyhoeddwyd: (1995)
• RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction
  gan: Ptasinska, Anetta, et al.
  Cyhoeddwyd: (2019)
• RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction
  gan: Ptasinska, Anetta, et al.
  Cyhoeddwyd: (2019)
• Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.
  gan: Meyers, S, et al.
  Cyhoeddwyd: (1993)
• Elevated PIN1 expression by C/EBPα-p30 blocks C/EBPα induced granulocytic differentiation via c-Jun in AML
  gan: Pulikkan, John A, et al.
  Cyhoeddwyd: (2010)