RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML

Acute myeloid leukemia (AML) is a heterogeneous disease caused by mutations in transcriptional regulator genes, but how different mutant regulators shape the chromatin landscape is unclear. Here, we compared the transcriptional networks of two types of AML with chromosomal translocations of the RUNX...

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主要な著者:	Justin Loke, Salam A. Assi, Maria Rosaria Imperato, Anetta Ptasinska, Pierre Cauchy, Yura Grabovska, Natalia Martinez Soria, Manoj Raghavan, H. Ruud Delwel, Peter N. Cockerill, Olaf Heidenreich, Constanze Bonifer
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2017-05-01
シリーズ:	Cell Reports
主題:	RUNX1-EVI1 RUNX1-ETO epigenetic landscape chromatin transcriptional network acute myeloid leukemia
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2211124717306113
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