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Dichotomy of AML1-ETO Functions: Growth Arrest versus Block of Differentiation
The fusion gene AML1-ETO is the product of t(8;21)(q22;q22), one of the most common chromosomal translocations associated with acute myeloid leukemia. To investigate the impact of AML1-ETO on hematopoiesis, tetracycline-inducible AML1-ETO-expressing cell lines were generated using myeloid cells. AML...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87279/ https://ncbi.nlm.nih.gov/pubmed/11463839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5577-5590.2001 |
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