Hematopoietic Stem Cell Expansion and Distinct Myeloid Developmental Abnormalities in a Murine Model of the AML1-ETO Translocation

Gelijkaardige items

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• Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.
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• Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins
  door: Barseguian, Karina, et al.
  Gepubliceerd in: (2002)
• RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis
  door: Yan, Ming, et al.
  Gepubliceerd in: (2009)
• Clonal evolution of AML1-ETO coexisting with BCR-ABL and additional chromosome abnormalities in a blastic transformation of chronic myeloid leukemia
  door: Ma, Cheng-Cheng, et al.
  Gepubliceerd in: (2020)