Hematopoietic Stem Cell Expansion and Distinct Myeloid Developmental Abnormalities in a Murine Model of the AML1-ETO Translocation

The t(8;21)(q22;q22) translocation, which fuses the ETO gene on human chromosome 8 with the AML1 gene on chromosome 21 (AML1-ETO), is one of the most frequent cytogenetic abnormalities associated with acute myelogenous leukemia (AML). It is seen in approximately 12 to 15% of AML cases and is present...

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Main Authors: de Guzman, Cristina G., Warren, Alan J., Zhang, Zheng, Gartland, Larry, Erickson, Paul, Drabkin, Harry, Hiebert, Scott W., Klug, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC133929/
https://ncbi.nlm.nih.gov/pubmed/12101243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.15.5506-5517.2002
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