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The p21(Waf1) pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO

The 8;21 translocation is a major contributor to acute myeloid leukemia (AML) of the M2 classification occurring in approximately 40% of these cases. Multiple mouse models using this fusion protein demonstrate that AML1-ETO requires secondary mutagenic events to promote leukemogenesis. Here, we show...

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Detalhes bibliográficos
Main Authors: Peterson, Luke F., Yan, Ming, Zhang, Dong-Er
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885483/
https://ncbi.nlm.nih.gov/pubmed/17284535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-012575
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