Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development

Normal blood-cell differentiation is controlled by regulated gene expression and signal transduction. Transcription deregulation due to chromosomal translocation is a common theme in hematopoietic neoplasms. AML1-ETO, which is a fusion protein generated by the 8;21 translocation that is commonly ass...

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Bibliographische Detailangaben
Hauptverfasser: Yan, Ming, Burel, Sebastien A., Peterson, Luke F., Kanbe, Eiki, Iwasaki, Hiromi, Boyapati, Anita, Hines, Robert, Akashi, Koichi, Zhang, Dong-Er
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC535382/
https://ncbi.nlm.nih.gov/pubmed/15569932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406702101
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