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Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development
Normal blood-cell differentiation is controlled by regulated gene expression and signal transduction. Transcription deregulation due to chromosomal translocation is a common theme in hematopoietic neoplasms. AML1-ETO, which is a fusion protein generated by the 8;21 translocation that is commonly ass...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535382/ https://ncbi.nlm.nih.gov/pubmed/15569932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406702101 |
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